Job Description

As a member of the new drug development team, you will participate in preclinical stage research, mainly responsible for pharmacology, toxicology, pharmacokinetics and other related studies, manage CRO, and promote the smooth transition of new drugs from the laboratory stage to clinical research. You will work closely with cross-functional teams to ensure the scientificity and compliance of the study, and help with project decision-making.

Main responsibilities

1. Pharmacological research

o Design and execute pharmacological experiments, evaluate the pharmacological effects, mechanism of action, etc. of candidate compounds;

2. Toxicological studies

o Design and implement in vitro and in vivo toxicology experiments to evaluate the safety of candidate compounds;

o Analyze toxicological data, identify potential risks, and propose safety improvement suggestions;

o Write and review toxicology-related reports to ensure compliance with GLP (Good Laboratory Practice) requirements.

3. Drug metabolism study

oResponsible for pharmacokinetic (ADME) studies, evaluating the absorption, distribution, metabolism, and excretion of compounds;

o Design drug pharmacokinetic experiments, analyze experimental data and prepare summary reports;

o Collaborate with clinical teams to provide data support for future clinical trials.

4. Literature review and technical support

o Track the progress of pharmacology, toxicology, and pharmacokinetics research, and evaluate the application potential of new technologies and methods;

o Provide technical support and answer related questions encountered in the R&D process.

5. Cross-departmental collaboration

o works closely with project management, clinical research, regulatory affairs, etc. to ensure that the study progresses smoothly;

o Regularly report progress to the project team and participate in related meetings and discussions.

Job Requirements

1. Educational requirements

oPharmacy, biology, chemistry, medicine or related professional master's degree or above.

2. Work experience

o At least 3 years of drug development experience in pharmacology, toxicology or pharmacokinetics, those with preclinical research experience in pharmaceutical companies or biopharmaceutical companies are preferred;

o Familiar with pharmacology, toxicology, pharmacokinetics (ADME) related research methods, and able to independently design experiments, analyze data, and write reports.

3. Professional skills

o Proficient in preclinical research-related experimental techniques, including in vitro and in vivo pharmacological, toxicological research methods;

o Familiar with the basic theory and experimental design of drug metabolism and pharmacokinetics (ADME);

o Familiar with GLP regulations, understand the compliance requirements of preclinical studies;

oHave good English listening, speaking, reading and writing skills, and be able to read and write English literature and reports.

4. Personal qualities

oStrong analysis and problem-solving skills, able to think independently and propose innovative solutions;

oGood team spirit, able to effectively communicate with interdisciplinary teams;

oStrong sense of responsibility and proactive attitude, able to maintain work quality under high pressure.